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17 Jul 2018
1. The highly polymorphic HLA alleles in humans reflect polymorphisms that have been conserved since before the divergence of humans and chimpanzees approximately 7.5 million years ago. Explain how this can be consistent with the observation that the most recent common ancestor of all human mitochondrial genomesâsometimes referred to as the Mitochondrial Eveâdates to around 200,000 years ago. (2-4 sentences).
2. Explain one method you might use to scan the human genome for the âsignature of selectionâ in order to identify interesting genes that have experienced selective pressure in particular populations. What data would you gather? How would you interpret the results? (1 paragraph).
1. The highly polymorphic HLA alleles in humans reflect polymorphisms that have been conserved since before the divergence of humans and chimpanzees approximately 7.5 million years ago. Explain how this can be consistent with the observation that the most recent common ancestor of all human mitochondrial genomesâsometimes referred to as the Mitochondrial Eveâdates to around 200,000 years ago. (2-4 sentences).
2. Explain one method you might use to scan the human genome for the âsignature of selectionâ in order to identify interesting genes that have experienced selective pressure in particular populations. What data would you gather? How would you interpret the results? (1 paragraph).
Trinidad TremblayLv2
19 Jul 2018