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23 Jun 2019
Leprosy is caused by infection with Mycobacterium Leprae. In one form of the disease, tuberculoid leprosy, few live bacteria are found and although the skin and peripheral nerves are damaged by inflammatory responses, the disease progresses slowly and the patient survives. In the other form, lepromatous leprosy, copious antibodies are produced but gross tissue destruction occurs and the disease is eventually fatal. Which form of CD4 cell response (Th1 or Th2) do you think is induced in each form of the disease and how does it contribute to the outcome?
Leprosy is caused by infection with Mycobacterium Leprae. In one form of the disease, tuberculoid leprosy, few live bacteria are found and although the skin and peripheral nerves are damaged by inflammatory responses, the disease progresses slowly and the patient survives. In the other form, lepromatous leprosy, copious antibodies are produced but gross tissue destruction occurs and the disease is eventually fatal. Which form of CD4 cell response (Th1 or Th2) do you think is induced in each form of the disease and how does it contribute to the outcome?
Hubert KochLv2
25 Jun 2019
