You identify a gene that controls fin size in zebrafish and after examining many fish you realize that in the population only two alleles exist for this gene. One allele is wild type leading to normal fins, and the other allele leads to small fins. Interestingly, only homozygous dominant individuals have a normal fin size, and all other individuals have small fins. What is the most likely explanation for the single-gene interaction of the fin alleles?
a. haplosufficient
b. complete dominance
c. codominant
d. haploinsufficient
e. recessive lethal alleles
You identify a gene that controls fin size in zebrafish and after examining many fish you realize that in the population only two alleles exist for this gene. One allele is wild type leading to normal fins, and the other allele leads to small fins. Interestingly, only homozygous dominant individuals have a normal fin size, and all other individuals have small fins. What is the most likely explanation for the single-gene interaction of the fin alleles?
a. haplosufficient
b. complete dominance
c. codominant
d. haploinsufficient
e. recessive lethal alleles
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Related questions
Problem B: Prairie Dog Population Genetics
A relatively stable population of Black-footed Prairie Dogs (70,000 individuals) lives in a national park in
Saskatchewan, Canada. These creatures have various tones of brown fur, but may have brown or auburn tails.
Furthermore, tails may be of solid color (brown or auburn) or be tipped with white or black fur. Three alleles for
tail coloration exist in this population. These alleles include:
| Allele | Trait | Notes on Phenotype and Relationship to other Alleles |
| T | White Tip | Tail has white fur at tip. Completely dominant over t; codominant with T* |
| t | Black tip | Tail has black fur at tip. Codominant with T*; recessive to T |
| T* | Auburn tail | Background tail color is auburn when T* is present. Codominant with T or t |
The frequency of the (T) allele in this population is 0.28, and the frequency of the (t) is 0.4.
Answer each of the following. Show all of your work/calculations. Cite your rationale if appropriate.
1. List and describe all the possible genotypes and their respective phenotypes for this gene system in the
population.
2. Using the Hardy-Weinberg theorem, calculate the probable frequency of animals with the following
phenotypes in this population:
⢠White tipped tails
⢠Black tipped auburn tails
3. What is the expected combined frequency of individuals carrying the TT, TT* and Tt genotypes in this
population?
4. How many (number, not percentage) of the prairie dogs would you expect to have black tipped, auburn
tails? Explain.
5. In a different population of 10,000 prairie dogs (South Dakota, USA), only the T and t alleles are found. If
this group included only 400 animals with black tipped, brown tails, what is the probable number (not
frequency) of individuals that are homozygous dominant (TT) in this herd?
