Question

Please, Mark correct answer of the multiple choice questions. Select only one answer, if any other indications are not present in the question. Write 2-3 sentences of explanation, why you selected this particular answer, or answer specific question if indicated.

1) Histone deacylase modulate gene transcription. Which sentence is incorrect?

A. HDAC removes acetyl group from histone’s lysine

B. HDAC has opposite effect to HAT

C. HDAC condensates chromatin and prevent transcription

D. HDAC decreases ability of histones to bind DNA

Explain:

2) In the absence of -mercaptoethanol (non-reduced conditions) protein migrate on SDS-PAGE with molecular weight approx. 90 kDa. In the presence of -mercaptoethanol (reduced conditions) on the gel appeared only one band in molecular weight resembled to 15 kDa. Which sentence described the best structure of this protein?

A. This could be only homohexamer

B. This could be only heterohexamer

C. This could be only homoheptamer

D. This could be homohexamer or heterohexamer

Explain: