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9 Apr 2019

* Bill is outside on a snowy day without a warm coat. His skin is ale and chille and he begins to shiver. Explain how these responses are attempts of his body to maintain homeostasis of temperature. What other responses might raise his body temperature?

* Arrange in order the events that occur in the production of a fever of 39.4​oC (103​oF) and recovery from this state

A. 39.4​oC temperature is reached and maintained.

B. Prostaglandins (PGs) cause the hypothalamic "thermostat" to be reet from normal 37.5​oC (98.6​oF) to a higher temperature such as 39.4​oC (103​oF).

C. Vasoconstriction and shivering occur as heat is conserved in order to raise body temperature to the 39.4​oC (10​3​oF) level ddirected by the hypothalamus.

D. Source of pyrogens is removed (for example, bacteria are killed by antibiotics), lowering hypothalamic "thermostat" to 37.5​oC (98.6​oF).

E. "Crisis" occurs. Obeying hypothalamic orders, the body shifts to heat loss mechanisms such as sweating and vasodilation, returning body temperature to normal.

F. Infectious organisms cause phagocytes to release interleukin-1, which then causes hypothalamic release of PGs.

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Irving Heathcote
Irving HeathcoteLv2
11 Apr 2019

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