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19 Aug 2019

There's a story going round the news about a baby that was,apparently, cured of HIV using a cocktail of drugs at an early age.The story piqued my interest, but details seem scarce. One of themain things I've seen being refuted about it is the difficulty inproving that (a) the child actually had HIV in the first place, and(b) that the child is really fully cured.

I've seen the following arguments:

  • Western Blot tests on young children are practically useless,since they test for antibodies. The child will likely haveantibodies passed down by the HIV+ mother, regardless of whetherthe child has HIV. The test will show the antibodies, which may bemistaken for an active immune response from the child. As such,there will be a high false-positive rate on such tests.
  • Using PCR to attempt to identify a lack of HIV is flawed, sinceit may lay dormant in a small colony of T-cells until a secondaryimmune response is triggered, causing a new outbreak. As such, itis very difficult to show that a patient is "cured".

Are these arguments valid? Are there any other reasons to besceptical about the claims? Any other information that might beuseful in understanding the case?

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Bunny Greenfelder
Bunny GreenfelderLv2
20 Aug 2019

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