18. Which of the following statements about a pedigree would be most definitive in differentiating an AD from an XLD pattern of inheritance?

A.
Affected males and females are seen in all generations.

B.
An affected male has only one daughter, and that daughter is affected.

C.
There are two instances where an uaffected parent has an affected parent and an affected child.

D.
An unaffected male with an affected father has three affected daugthers.

E.
An unaffected mother with an affected mother has one affected daughter and one affected son.

20. If a man and his maternal uncle express an X-linked recessive disease, we can draw the following conclusion(s):

A.
His maternal grandma was a carrier

B.
All of his maternal uncles must be affected

C.
All of his daughters will be carriers

D.
All of his sisters are carriers

E.
All of his maternal aunts are carriers

F.
A and C

G.
A and D

Question

18. Which of the following statements about a pedigree would be most definitive in differentiating an AD from an XLD pattern of inheritance?

	A.	Affected males and females are seen in all generations.
	B.	An affected male has only one daughter, and that daughter is affected.
	C.	There are two instances where an uaffected parent has an affected parent and an affected child.
	D.	An unaffected male with an affected father has three affected daugthers.
	E.	An unaffected mother with an affected mother has one affected daughter and one affected son.

20. If a man and his maternal uncle express an X-linked recessive disease, we can draw the following conclusion(s):

	A.	His maternal grandma was a carrier
	B.	All of his maternal uncles must be affected
	C.	All of his daughters will be carriers
	D.	All of his sisters are carriers
	E.	All of his maternal aunts are carriers
	F.	A and C
	G.	A and D

Unlock all answers

	A.	An unaffected individual in an XLD pedigree with complete penetrance
	B.	An individual who displays the recessive phenotype of a Mendelian trait
	C.	An individual with curly hair (Incomplete dominance)
	D.	An affected male with red-green color blindness (XLR)
	E.	An affected male with a Y-linked trait
	F.	An unaffected teenage child of an affected individual with Huntington (AD), in a population with complete penetrance of this disorder
	G.	An unaffected individual who has an affected parent and an affected child in a pedigree with incomplete penetrance

	A.	Johnâs mother was affected, and transmitted the trait to John.
	B.	Johnâs maternal grandmother was affected
	C.	Johnâs maternal aunt should be affected
	D.	All of Johnâs sibs should be affected
	E.	There is no chance for any of John's nephews to be affected.

	A.	A woman homozygous affected with Duchenne
	B.	A woman homozygous affected with red-green color blindness
	C.	An XYY boy affected with Duchenne
	D.	A woman affected with red-green color blindness who has a normal father and a carrier mother
	E.	A homozygous individual for Dimples

	A.	Males and females with the same genotypes may have different phenotypes.
	B.	They can be seen only in one of the sexes, and that is the sex in which, the pattern of inheritance of the trait is dominant.
	C.	A male can inherit the allele of these traits from either of his parents.
	D.	Regardless of the sex of the parent, alleles of these traits can be equally transmitted to sons and daughters
	E.	Their phenotypic expression depends on the sex hormones