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29 Nov 2018
Both phospholipids and proteins are asymmetrically located in cell membranes - meaning the outer half and the inner half of the bilayer contain different phospholipids and the proteins have a cytoplasmic side and an "out" side. When detergents are used to disrupt the membrane, creating a water soluble mixture of lipids and proteins, and then the detergents are removed by dialysis, the lipid bilayer will reform spontaneously. Except now the asymmetry is gone and both proteins and lipids are located randomly in the newly formed membrane. What does this tell you about how the cell synthesizes cellular membranes?
Both phospholipids and proteins are asymmetrically located in cell membranes - meaning the outer half and the inner half of the bilayer contain different phospholipids and the proteins have a cytoplasmic side and an "out" side. When detergents are used to disrupt the membrane, creating a water soluble mixture of lipids and proteins, and then the detergents are removed by dialysis, the lipid bilayer will reform spontaneously. Except now the asymmetry is gone and both proteins and lipids are located randomly in the newly formed membrane. What does this tell you about how the cell synthesizes cellular membranes?
Deanna HettingerLv2
29 Nov 2018