3. The malaria control team in a given area has access to 5 different drugs, chloroquine, mefloquine, pyrimethamine, amodiaquine, and artimisinin. Nothing else will be available for the foreseeable future. Some resistance to all 5 is already observed.
A) Provide a strategy to maximize the time you can cure malaria using these 5 drugs. Explain why you want to use this strategy (what is the idea behind your plan), and be precise: when do you plan to use what drugs. What are the potential problems you can face and how do you plan to deal with them? Remember, you are working with humans, not robots.
B) Hypnozoites are forms of P. vivax and P. ovale that are dormant, with barely any metabolic activity. After long periods of time (months, a year), they can be re-activated start invading red blood cells, and causing malaria. Explain why artemisinin would or would not be a good drug for people suspected of carrying hyponozoites.
3. The malaria control team in a given area has access to 5 different drugs, chloroquine, mefloquine, pyrimethamine, amodiaquine, and artimisinin. Nothing else will be available for the foreseeable future. Some resistance to all 5 is already observed.
A) Provide a strategy to maximize the time you can cure malaria using these 5 drugs. Explain why you want to use this strategy (what is the idea behind your plan), and be precise: when do you plan to use what drugs. What are the potential problems you can face and how do you plan to deal with them? Remember, you are working with humans, not robots.
B) Hypnozoites are forms of P. vivax and P. ovale that are dormant, with barely any metabolic activity. After long periods of time (months, a year), they can be re-activated start invading red blood cells, and causing malaria. Explain why artemisinin would or would not be a good drug for people suspected of carrying hyponozoites.
