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16 May 2018
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QUESTION 1
The pentose phosphate shunt is a pathway required for the
formation of ribose-5-phosphate used in the synthesis of nucleic acids
production of ATP by oxidative phosphorylation
production of NADPH to drive various anabolic synthetic pathways
regulation of gluconeogenesis
QUESTION 2
The TCA cycle is regulated by
succinyl-CoA levels
ADP
NADH
Fe2+
QUESTION 3
The TCA cycle produces
substrate level phosphorylation of ADP to ATP
Reduction of NAD+ to NADH
substrate level phosphorylation of GDP to GTP
Reduction of FAD to FADH2
Multiple or none can be the answers!
QUESTION 1
The pentose phosphate shunt is a pathway required for the
formation of ribose-5-phosphate used in the synthesis of nucleic acids | ||
production of ATP by oxidative phosphorylation | ||
production of NADPH to drive various anabolic synthetic pathways | ||
regulation of gluconeogenesis |
QUESTION 2
The TCA cycle is regulated by
succinyl-CoA levels | ||
ADP | ||
NADH | ||
Fe2+ |
QUESTION 3
The TCA cycle produces
substrate level phosphorylation of ADP to ATP | ||
Reduction of NAD+ to NADH | ||
substrate level phosphorylation of GDP to GTP | ||
Reduction of FAD to FADH2 |
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Hubert KochLv2
17 May 2018
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Fill in the blank in the following table:
metabolic cycle | location pro/ eukaryote | components | substrates | products | pathway purpose |
embden- meyerhof- parnas (glycolysis) | cytoplasm/ cytoplasm | 10 enzymes | |||
pentose phosphate pathway | cytoplasm/ cytoplasm | dozen enzyme | 1 Glucose (6 carbon), 1 NADP, 1ATP | 1 Ribose-P (5 carbon) + 1CO2, 1NADPH, or sugars, 1 ADP | Nucleotide synthesis, NADPH for anabolism |
PDH reaction | cytoplasm/ mitochondria matrix | ||||
TCA/ Krebs/ citric acid cycle | generation of high energy electron carriers, provide metabolic precursors | ||||
Electron transport chain + ATP synthase (aerobic respiration) | |||||
Electron transport chain + ATP synthase (anaerobic respiration) | 1Nitrate or sulfate or CO2, 1NADH + ____ ADP Or 1FADH2+ ____ ADP | N2, or NO2 or H2S or CH4 1NAD + ____ ATP Or 1FADH2+ ____ ATP | Generate proton motive forces abd use to generate ATP regenerate NAD+ | ||
Fermentation | cytoplasm/ cytoplasm | 1 or more enzymes (vary by organism) | 1 pyruvate, 1 NADH | 1 alcohol or acid (maybe 1 CO2) NAD+ | Regenerate NAD+ |