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22 Jun 2018

The restriction of homology-directed repair to S and G2 phase of the cell cycle is dependent on phosphorylation of which of the following proteins?

(A) CtIP

(B) DNA-PKcs

(C) Artemis

(D) Rad51

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Related questions

state of DNA inside the cell. Specify the stateof DNA ( chromatin or condensed chromosome) in each phase andsub-phase of the cell cycle:

g1

S

g2

mitosis

cytokinesis

2) Explain how cyclin, cycling dependent kinase become MPF andhow that induces the cell to cross a cell cycle checkpoint ( Key:remember the 2 cellularmechanisms by which proteins acquire newfunctions).

Which of the following steps activates MPF for G2 to M phase transition ?

a) Phosphorylation of Cdc2

b) Phosphorylation of Cdk 4/6

c) Phosphorylation of Cdc25

d) Phosphorylation of CAK

e) Phosporylation of Wee 1

Which of the following enzymes involved in G2 to M phase transition inactivates MPF?

a) Cdc2

b) Cdk 4/6

c) Cdc25

d) CAK

e) Wee 1

Which of the following components of MPF is responsible for the actual phase transition of G2 to M?

a) Cdc2

b) Cyclin E

c) Cdk 4/6

d) Cdc25

e) Cyclin B

(A) What is the correct order of cell cycle phases? Select one:

a. G1 to S to G2 to M phase b. M to G2 to S to G1 phase c. none of these d. G1 to G2 to S to M phase e. G1 to M to S to G2 phase

(B) What cyclin-cdk complex is critical in mitosis? Select one:

a. Cyclin E - cdk2 b. cyclin E - cdk1 c. cyclin A - cdk 2 d. cyclin B - cdk1 e. cyclin D cdk 4

(C) Which of the following proteins is progressively phosphorylated throughout the cell cycle from G1 through to M phase? Select one:

a. E2F1 b. pRb c. RNA polymerase II d. cyclin D e. cyclin B

(D) An antibody generated from a mouse hybridoma cell line is called a mouse ________. Select one:

a. anticlonal antibody b. polyclonal antibody c. synclonal antibody d. none of these answers e. monoclonal antibody

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