Describe the building blocks and synthesis reactions of the bacterial peptidoglycan.

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Lelia LubowitzLv2

4 Jan 2019

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Match these proteins to their function in bacterial replication.

1) FTsZ

2) ZipA

3) MreB

a) actin-related proteins, contibutes to rod-shaped and organization of peptidoglycan synthesis

b) actin-related protein, attaches Z-ring to cytoplasmic membrane

c) tubulin-related GTPase, component of Z-ring

Where does the name âpeptidoglycanâ come from? What features of peptidoglycan structure help make Bacterial cell walls rigid? Is peptidoglycan likely to denature if a cell is placed in boiling water? (hint: why do proteins and double-stranded DNA denature when heated?)

The following is a list of antibiotics or enzymes that attack peptidoglycan or inhibit its synthesis. For each antibiotic indicate the step in synthesis they inhibit or how it attacks peptidoglycan.

a- Penicillin (Î²-lactam) family -

b- Cephalosporins -

c- Bacitracin -

d- Vancomycin -

e- D-Cycloserine-

f- Lysozyme-