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1 May 2019

After glycolysis and before the citric acid cycle (TCA), the pyruvate dehydrogenase complex breaks down the pyruvate to three separate components; a carboxyl group, a two-carbon fragment, and coenzyme A (CoA). What happens next to these products?

a. The carboxyl group is reduced and released as CO2, the two-carbon fragment is used to reduce NADH, and CoA is converted to acetyl CoA for the TCA.

b. The carboxyl group is oxidized and released as CO2, the two-carbon fragment is used to oxidize NAD+, and CoA is converted to acetyl CoA for glycolysis.

c. The carboxyl group is used to reduce NAD+, the two-carbon fragment is oxidized and released as CO2, and CoA is oxidized to acetyl CoA for oxidative phosphorylation the TCA.

d. The carboxyl group is oxidized and released as CO2, the two-carbon fragment is used to reduce NAD+, and CoA is converted to acetyl CoA for the TCA.

e. The carboxyl group is used to oxidize NAD+, the two-carbon fragment is reduced and released as CO2, and CoA enters the TCA.

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Nestor Rutherford
Nestor RutherfordLv2
2 May 2019

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