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If the proportion of an African population that are carriers of the Sickle Cell allele (HbS) is 0.127, what is the HbS allele frequency in the population? NOTE: You may get more than one solution for this question. If so, choose the smaller frequency.

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7 Jun 2023

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Related questions

Rank the following terms in increasing order of scale accordingto your knowledge of their definitions:

-Locus
-Allele
-Chromosome
-Gene

If 16% of a population expressed a recessive trait, whatpercentage of the gene pool is the dominant allele?

Consider a population of Peach-faced lovebirds where:

65% of all gametes carry a dominant allele (F)for regular plumage (feather colors).

The remaining 35% carry the recessive allele(f) for a plumage with white.

When two heterozygous (Ff) individuals breed,we expect the genotype Ff to account for_____% ofthe new generation.

In the case of a species of sea lions displaying assortativemating (where individuals prefer to mate with individuals that looklike them), the conditions for Hardy-Weinberg Equilibrium are stillmet and supported (T or F)

If 90% of the alleles in a population are dominant, what is theratio of genotypes?

What are genes comprised of?

In the Hardy-Weinberg equation, what does 2pq denote?

Without strong natural selection, recessive alleles willinevitable disappear from a population T or F

If the proportion of sickle-cell sufferers(HbS-HbS homozygotes) in a population is 0.04,according to the Hardy-Weinberg equation, what is the proportion ofsickle-cell carriers (HbS-HbA heterozygotes) in thatpopulation?

coralherring96

Q49. Which of the following is NOT true?

If a genetic disease reduces fertility and the allele thatcauses the disease offers no other advantage, the allele willlikely eventually disappear, due to natural selection.

Natural selection does not favor individuals who are homozygousfor the sickle-cell allele, because these individuals typically diebefore they are old enough to reproduce.

Individuals who are heterozygous HbA/HbS areprotected from malaria, and this is why sickle-cell diseasepersists in wetter, mosquito-prone regions in Africa.

In regions where malaria does not occur, individuals who areheterozygous HbA/HbS have a fitness advantageover those who are homozygous for the normal hemoglobin allele(HbA).

Q50. AFTER malaria is cured, the frequency of the HbSallele should decrease in regions with lots of mosquitoesbecause:

People will no longer die from sickle-cell disease in theseregions.

Having one copy of the HbS allele will no longer beadvantageous in these regions.

Natural selection will no longer act on the HbS alleleat all in these regions.

All alleles associated with genetic diseases eventuallydisappear.

Q52. If the frequency ofthe HbS allele is 0.4 in a population, what is thefrequency of the HbAallele (assuming this is atwo-allele system)?

Q53. Which of the following would be sufficient for theHardy-Weinberg equation to accurately predict genotype frequenciesfrom allele frequencies?

p + q = 1

The population is not evolving due to natural selection.

The population is not evolving due to any of the conditions thatdisrupt Hardy-Weinberg equilibrium.

The population is infinitely large.

Q54. In a village, if the proportion of individuals who havesickle-cell disease is 0.25, and the population is assumed to be atHardy-Weinberg equilibrium, what is the expected frequency of theHbS allele? (Hint: What is the genotype of people withsickle-cell disease, and how is that genotype represented in theHardy-Weinberg equation?)

0.1250.250.50.75

Q55. In the same village, what proportion of the populationshould be heterozygous HbA/HbS, according to theHardy-Weinberg equation?

Use the following passage to answer the nextthree questions.

It has been hypothesized that people who are heterozygous forthe allele that causes the deadly genetic condition cystic fibrosis(which, among other symptoms, reduces fertility) are more resistantto the deadly disease tuberculosis.

Q56. If the cystic fibrosis allele protects against tuberculosisthe same way the sickle-cell allele protects against malaria, thenwhich of the following should be true of a comparison betweenregions with and without tuberculosis?

Cystic fibrosis deaths should be more common in regions withtuberculosis.

Cystic fibrosis deaths should be less common in regions withtuberculosis.

Cystic fibrosis deaths should be equally common in both types ofregions.

Regional differences in the cystic fibrosis death rate should bepurely random and unpredictable.

Q57. A person who is heterozygous for the cystic fibrosis allelemoves to a small, isolated community where no one previouslycarried the allele. If the cystic fibrosis allele protects againsttuberculosis the same way the sickle-cell allele protects againstmalaria, what should happen to the frequency of the cystic fibrosisallele in the community over time, and why?

The cystic fibrosis allele should disappear from the population,because a single individual with the allele is not enough for it toproliferate.

The cystic fibrosis allele should increase to a relatively highfrequency, because heterozygotes with the allele will be morelikely to survive than others.

The cystic fibrosis allele should become fixed in thepopulation, due to genetic drift.

The cystic fibrosis allele should either disappear or increasein frequency, depending on chance as well as on tuberculosisprevalence and death rate.

Use the following additional passage to answer the nextquestion.

Suppose you travel to the future, to a time when neithercystic fibrosis nor tuberculosis have caused any deaths for manygenerations. In all of these future populations, thecystic fibrosis allele still exists at a low frequency.

Q58. You visit a huge city with millions of people. If you wereto start sampling the cystic fibrosis allele from one generation tothe next, what should happen to its frequency over the next fewgenerations, and why?

The allele frequency should change a lot from one generation tothe next due to random genetic drift.

The allele frequency should not change much from one generationto the next because the population is large.

The allele frequency should steadily increase due to naturalselection.

The allele frequency should steadily decrease due to naturalselection.

amaranthherring501

A human gene called the Î²-globin gene encodes a polypeptide that functions as a subunit of the protein known as hemoglobin. Hemoglobin is found within red blood cells; it carries oxygen. In human populations the Î²-globin gene can be found as the common allele known as Hb^A, and it can also be as the Hb^S allele. Individuals who have two copies of the Hb^S allele have the disease called sickle cell disease. Are the following examples descriptions of genetics at the molecular, cellular, organism, or population level?

A. The Hb^Sallele encodes a polypeptide that functions slightly differently from the polypeptide encoded by the Hb^Aallele.

B. If an individual has two copies of the Hb^Sallele, that persons red blood cells take on a sickle cell shape.

C. Individuals who have two copies of the Hb^Aallele do not have sickle cell disease, but are not resistant to malaria. People who have one Hb^Aallele and one Hb^S allele do not have sickle cell disease but are resistant to malaria. People who have two copies of the Hb^Sallele have sickle cell disease, and this disease may significantly shorten their lives.

D. Individuals with sickle cell disease have anemia because their red blood cells are easily destroyed by the body.