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6 Nov 2019
Provide a complete retrosynthesis and forward synthesis of the target molecule below from the given starting materials. All carbons of the target must be from the given starting materials. You may use any reagents you find necessary. You may include more than one step over a reaction arrow, but please no more than 3 steps at a time. Please show the key intermediates in your synthesis for partial credit. (10 bonus points) 1. For full credit, include a retrosynthetic analysis, complete forward synthesis showing all transformations and key intermediates along the way. Use our current 2510 reactions. Do consider reaction selectivity including regioselectivity, stereoselectivity, and chemoselectivity. More than 10 points may be awarded if you create a more efficient synthesis than Dr. B or the TAs. Me +CH2N2 Me Me Me Br target molecule starting materials Retro Tip: Keep in mind which bonds you need to form and which atom needs to have the functionality in order to make that happen. You must account for the specific stereochemistry at the indicated positions (yes, the enantiomer/diastereomers will also be created.... Show transcribed image text
Provide a complete retrosynthesis and forward synthesis of the target molecule below from the given starting materials. All carbons of the target must be from the given starting materials. You may use any reagents you find necessary. You may include more than one step over a reaction arrow, but please no more than 3 steps at a time. Please show the key intermediates in your synthesis for partial credit. (10 bonus points) 1. For full credit, include a retrosynthetic analysis, complete forward synthesis showing all transformations and key intermediates along the way. Use our current 2510 reactions. Do consider reaction selectivity including regioselectivity, stereoselectivity, and chemoselectivity. More than 10 points may be awarded if you create a more efficient synthesis than Dr. B or the TAs. Me +CH2N2 Me Me Me Br target molecule starting materials Retro Tip: Keep in mind which bonds you need to form and which atom needs to have the functionality in order to make that happen. You must account for the specific stereochemistry at the indicated positions (yes, the enantiomer/diastereomers will also be created....
Show transcribed image text Patrina SchowalterLv2
26 May 2019