mine formation The following is an example of a Pictet-Spengler reaction. This reaction combines an i reaction with an electrophilic aromatic substitution. 17) Meo 1) AcOH 2) HCI, heat a) The product after step (1) is an imine. Propose the structure of this imine below. (4 poirn ts) b) Provide a mechanism for the overall transformation. Show the formation of the imine and the cyclization. Be sure to use the correct arrow notation, and include relevant formal charges and lon pairs. (10 points)
Show transcribed image textmine formation The following is an example of a Pictet-Spengler reaction. This reaction combines an i reaction with an electrophilic aromatic substitution. 17) Meo 1) AcOH 2) HCI, heat a) The product after step (1) is an imine. Propose the structure of this imine below. (4 poirn ts) b) Provide a mechanism for the overall transformation. Show the formation of the imine and the cyclization. Be sure to use the correct arrow notation, and include relevant formal charges and lon pairs. (10 points)