How do you do the stochiometry for this multistep synthesis?? Thank you!
Procedure 1) After having your synthetic scheme approved by your lab instructor, obtain your "free" grams of yor requested starting material, which will contain approximately 1 gram of the compound(s). Additional grams of starting material can be "bought" at a "price" of two points on your write-up sheet 2) Carry out the necessary reactions to prepare your target molecule. 3) Since each target molecule will require at least two steps to prepare, you may wish to verify the ider of the product of your first step by melting point before proceeding on with the second step of your synthesis. 4) Obtain a melting point of your final product, as well as literature melting point data for the same compound. Submit this information as part of your write-up sheet. Safety Considerations /Waste Disposal: See individual Safety Considerations / Waste Disposal sections on each experimental procedure Place your final product in the bottle labeled, "Products from Multi-Step Synthesis Experiment." Before leaving lab: Clean up the area around your lab station (wipe up any spills, etc.). o H 62 aceh borounde 0 aid uses 127
Show transcribed image textProcedure 1) After having your synthetic scheme approved by your lab instructor, obtain your "free" grams of yor requested starting material, which will contain approximately 1 gram of the compound(s). Additional grams of starting material can be "bought" at a "price" of two points on your write-up sheet 2) Carry out the necessary reactions to prepare your target molecule. 3) Since each target molecule will require at least two steps to prepare, you may wish to verify the ider of the product of your first step by melting point before proceeding on with the second step of your synthesis. 4) Obtain a melting point of your final product, as well as literature melting point data for the same compound. Submit this information as part of your write-up sheet. Safety Considerations /Waste Disposal: See individual Safety Considerations / Waste Disposal sections on each experimental procedure Place your final product in the bottle labeled, "Products from Multi-Step Synthesis Experiment." Before leaving lab: Clean up the area around your lab station (wipe up any spills, etc.). o H 62 aceh borounde 0 aid uses 127
4. After 10 minutes of drying Warren Worthington notices a severe melting point depression for his benzoic acid sample (80-100 °C) though he should have distilled off all the methanol. He calculates a 115% yield. Offer a reasonable explanation for the observed melting point depression, and unreasonable percent yield. What would you advise Warren to do in order to obtain reasonable data? (20 pts).
5. The hydrolysis of methyl benzoate is performed using a strong base (NaOH) as a catalyst, to form the corresponding carboxylic acid. During Step 11 of this procedure concentrated hydrochloric acid (HCl) is added to obtain the product as a white precipitate. Explain why HCl is added to form the solid. (10 pts)
6. Jean Grey is performing the hydrolysis of methyl benzoate, however after Step 11 she chooses to extract the product out using diethyl ether via liquid/liquid extraction. She realizes that residual methanol will be present in her sample now. What equipment in the lab can she use to remove the methanol, as well as the diethyl ether? What should she add to her flask to ensure she removes the water?(20 pts)
7. In principle it is possible to synthesize methyl benzoate again from the benzoic acid obtained in lab at 100% yield. To do this reaction NaOH and methanol can be used once again, however in order to obtain 100% yield water cannot be present during the reaction. Explain this using the equilibrium expression below. (Hint: It will be helpful to review Le Chatlierâs principle, and use this in your explanation) (25 pts)
Scheme1: Equilbrium of the fisher esterification of benzoic acid to form methyl benzoate.
8. Alex Summers accidentally breaks the container of hydrochloric acid in his fume hood. What are the proper safety protocols that he should follow? (10 pts)
