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10 Nov 2019
Ibuprofen is the active ingredient in Motrin, Nuprin, and Advil. It is currently sold racemic mixture although the S enantiomer is the active pain reliever and the R enantiomer is inactive. Draw 3D pictures of these two enantiomers. Label the chiral carbons to indicate which enantiomer is the R and which is the S. You don't need to show the 3D structure of the entire molecule, just the stereocenters. Explain why there are different physiological effects with the different enantiomers of ibuprofen. Can you tell, just by inspecting the ibuprofen enantiomers. which one will be dextrorotatory and which will be levorotatory? How might you distinguish between the two isomers of ibuprofen in the lab? Draw all the stereoisomers of 2, 3-dibromobutane. Which are enantiomers? Which are diastereomers? Are any identical/meso? Classify the following as "optically active" or "optically inactive." A solution of 1 - iodohexane A solution of (S) - 2-iodohexane A solution of 40% (S) - 3 - chlorohexane and 60% (R) - 3 - chlorohexane A solution of equal quantities of R and S 3-chlorohexane
Ibuprofen is the active ingredient in Motrin, Nuprin, and Advil. It is currently sold racemic mixture although the S enantiomer is the active pain reliever and the R enantiomer is inactive. Draw 3D pictures of these two enantiomers. Label the chiral carbons to indicate which enantiomer is the R and which is the S. You don't need to show the 3D structure of the entire molecule, just the stereocenters. Explain why there are different physiological effects with the different enantiomers of ibuprofen. Can you tell, just by inspecting the ibuprofen enantiomers. which one will be dextrorotatory and which will be levorotatory? How might you distinguish between the two isomers of ibuprofen in the lab? Draw all the stereoisomers of 2, 3-dibromobutane. Which are enantiomers? Which are diastereomers? Are any identical/meso? Classify the following as "optically active" or "optically inactive." A solution of 1 - iodohexane A solution of (S) - 2-iodohexane A solution of 40% (S) - 3 - chlorohexane and 60% (R) - 3 - chlorohexane A solution of equal quantities of R and S 3-chlorohexane
Irving HeathcoteLv2
7 Jul 2019