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10 Nov 2019
The Fischeresterification mechanism is examined. PART 1
The Fischer esterification mechanism is examined in the following two questions in the assignment. Part 1 involves MeOH addition to form the key tetrahedral intermediate. Part 2 will involve loss of H2O to form the ester. Final products of the overall reaction (ungraded): For all remaining steps in the mechanism: Draw each species (organic and inorganic) resulting from the previous step. Each step will include all of, and only, the atoms given in the first step (i.e., do not use extra reagent molecules/ions, and do not omit spectator ions). Box 2 J Include charges and nonbonding electrons. Add curved arrows for the forward reaction. Note: proton transfers must be drawn out explicitly. Show no more than one H+ transfer in any one step; all H+ transfers are intermolecular.
The Fischeresterification mechanism is examined. PART 1
The Fischer esterification mechanism is examined in the following two questions in the assignment. Part 1 involves MeOH addition to form the key tetrahedral intermediate. Part 2 will involve loss of H2O to form the ester. Final products of the overall reaction (ungraded): For all remaining steps in the mechanism: Draw each species (organic and inorganic) resulting from the previous step. Each step will include all of, and only, the atoms given in the first step (i.e., do not use extra reagent molecules/ions, and do not omit spectator ions). Box 2 J Include charges and nonbonding electrons. Add curved arrows for the forward reaction. Note: proton transfers must be drawn out explicitly. Show no more than one H+ transfer in any one step; all H+ transfers are intermolecular.
Hubert KochLv2
26 May 2019