1. Enalapril, shown below, is an important medicine for treatment of high blood pressure. a) One of the chirality centers in enalapril is marked with an asterisk. Identify the two other chirality centers and draw the fourth bond at each of these centers, clearly showing the stereochemistry. (2 marks) b) Draw (i) the enantiomer and (ii) one diastereomer of this molecule. (2 marks) c) Assign the configuration of the chirality center marked with an asterisk, using the Cahn-Ingold-Prelog Rules, briefly outlining the method you used.
1. Enalapril, shown below, is an important medicine for treatment of high blood pressure. Enalapril Ph a) One of the chirality centres in enalapril is marked with an asterisk. Identify the two other chirality centres and draw the fourth bond at each of these centres, clearly showing the stereochemistry (2 marks) (2 marks) Assign the configuration of the chirality centre marked with an asterisk, using the Cahn-Ingold-Prelog (5 marks) b) Draw (i) the enantiomer and (ii) one diastereomer of this molecule c) Rules, briefly outlining the method you used.
