On electrophilic substitution, the electrophiles will attack on the nitrogen atom in pyridine ring, will not prefer meta carbon position. Because nitrogen is more nucleophilic than Carbon. The electrophilic substitution like bromination can be done by activating pyridine ring with oleum at 1300c . On electrophilic substitution, the attack will be on the meta position. Because in the resonance structure of pyridine both ortho and meta postions are electrophilic, while meta position is nucleophilic. (Note: only by drawing the structure of pyridine, it will be more understandable)
Question-2
Gas chromatography â mass spectrometer(GC-MS) is a spectrophotometer used in organic chemistry to identify or to detect the elements present in a particular sample. It will help to identify the compound or an unknown sample, from the gas chromatograph obtained from GC MS. It will determine the molecular formula of compound.
Comment
Q1 can you draw?
Pyridine is very resistant to electrophilic aromatic substitution such as nitration and bromination, and undergoes reaction only under conditions. Please provide the explanation, and where is the position of electrophile attack when substitution does occur (10%). drastic
