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16 Nov 2019
Can someone please help me synthesize the following compounds?
The first problem entails synthesizing the following molecule by a series of steps from the trijodoarene. Two new reactions that are required in the synthesis are shown below. The first is called the ra coupling reaction where an alkyne is added to an arene under palladium metal mediated reaction conditions. The Pauson-Khand reaction is shown in the second sequence were an ene starting material is treated with digobaltoctacarbonyl to make the bicyclic ketone product. Use these steps and others to make the desired compound showing all steps in your synthesis.
Can someone please help me synthesize the following compounds?
The first problem entails synthesizing the following molecule by a series of steps from the trijodoarene. Two new reactions that are required in the synthesis are shown below. The first is called the ra coupling reaction where an alkyne is added to an arene under palladium metal mediated reaction conditions. The Pauson-Khand reaction is shown in the second sequence were an ene starting material is treated with digobaltoctacarbonyl to make the bicyclic ketone product. Use these steps and others to make the desired compound showing all steps in your synthesis.
Jean KeelingLv2
22 Jul 2019