Hello, can someone please help this poor mentally unstable college student. Much appreciated.
Case Study: Inhibition of Alcohol Dehydrogenase The patient While working in the ER, a patient was admitted with the following symptoms: nausea, poor coordination, blurry vision, abdominal cramping. After some questioning, you found out that the patient accidentally drank some fuel from a car used in the Indy race. The fuel is pure methanol and the patient is suffering from methanol toxicity Background on methanol toxicity In our body, when we consume alcoholic beverage, the enzyme alcohol dehydrogenase (ADH) is the one responsible for catalyzing the conversion of ethanol (in our alcoholic beverages) to acetaldehyde. ADH Ethanol Acetaldehyde It turns out that the enzyme has a rather broad substrate scope. In addition to ethanol, ADH can also convert methanol and ethylene glycol into very toxic products. For example, ADH converts methanol to formaldehyde, which is toxic to the optic nerve and can produce blindness. ADH CH OH Methanol Formaldehyde Questions I. What type of reaction is ethanol to acetaldehyde, is it a substitution, elimination, hydrolysis, oxidation, reduction, or acid/based? How about methanol to formaldehyde? 2. What class of enzyme is ADH? (Is it lyase, ete)? 3. Please answer the following questions about ADH a. What is the effect of ADH on the activation energy b. What is the effect of ADH on the rate of a reaction? c. What is the effect of ADiH on the thermodynamie parameter of a reaction? of a reaction?
