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19 Nov 2019
Please, draw the complete mechanism for these reactions. Thanks
stable as C=N) H20 (1 equiv) HCI (catalytic) THF mol. Sieves HO (dimethylacetal is more sterically- hindered, can be selectively opened!) HCI (catalytic) H20 THF mol. Sieves 25 °C andN endocyclic enamine favored HCI (1.1 equiv.) HN H20 / THF 65 °C HO NH3 with catalytic acid, cyclic hemiaminal would be part of product equilibirum using stoichiometric strong acid would help drive the reaction
Please, draw the complete mechanism for these reactions. Thanks
stable as C=N) H20 (1 equiv) HCI (catalytic) THF mol. Sieves HO (dimethylacetal is more sterically- hindered, can be selectively opened!) HCI (catalytic) H20 THF mol. Sieves 25 °C andN endocyclic enamine favored HCI (1.1 equiv.) HN H20 / THF 65 °C HO NH3 with catalytic acid, cyclic hemiaminal would be part of product equilibirum using stoichiometric strong acid would help drive the reaction
Jean KeelingLv2
7 Sep 2019