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11 Dec 2019
In considering active transport by Na+-K+-ATPase, 3 Na+ arepumped out of the cell and 2
K+ are pumped in for each ATP that is hydrolyzed to ADP + Pi. Giventhat the ?G for ATP hydrolysis is -10
kcal/mol, and that V is -60 mV, and that the pump typicallymaintains the internal Na+ at 10mM, external Na+ at
145 mM, internal K+ at 140 mM and external K+ at 5mM, what is theefficiency of the pump (i.e., what fraction
of the energy available from ATP hydrolysis is used to drivetransport)?
In considering active transport by Na+-K+-ATPase, 3 Na+ arepumped out of the cell and 2
K+ are pumped in for each ATP that is hydrolyzed to ADP + Pi. Giventhat the ?G for ATP hydrolysis is -10
kcal/mol, and that V is -60 mV, and that the pump typicallymaintains the internal Na+ at 10mM, external Na+ at
145 mM, internal K+ at 140 mM and external K+ at 5mM, what is theefficiency of the pump (i.e., what fraction
of the energy available from ATP hydrolysis is used to drivetransport)?