PSYB65H3 Study Guide - Final Guide: Neurotransmitter Receptor, Anxiolytic, Temporal Lobe
Document Summary
Lecture 7 mechanisms of drug action, psychopharmacology of neural stimulants (chapter 9, 15) A concept that if a drug is taken repeatedly, most drugs show a decreasing behavioural effect: basically, the more you take the drug, the less behavioural effect it has. If you"re using something that slows the system down (like a depressant), you"re getting under-activity of the system, then the system will compensate by increasing the number or sensitivity of the receptors. It"s never permanent on the brain, cyanide is permanent. Whenever a drug (ex. stimulant) is taken normally, it will cause excess amounts of transmitters to be released due to different mechanisms winds up with more transmitter substances stimulating the postsynaptic neurons (receptors) As more and more neurotransmitters are released and there is hyper-stimulation of the receptors, receptors are bombarded; there is classic response from postsynaptic receptor that will result in the reduce the number of sensitive of the postsynaptic receptors.