BIOL 1111 Lecture Notes - Cell Cortex, Centrosome, Separase

• School: University of Windsor
• Department: Biological Sciences
• Course: BIOL 1111
• Professor: Habetler

Document Summary

Interphase dna is replicated (s phase: g1 and g2 phases cell growth, m phase nuclear division (mitosis) and cell division (cytokinesis) M phase: chromosome condensation, then specialized cytoskeletal machines pull the chromosomes apart (mitotic spindle, finally the cell is split in half (contractile ring) Kinetochore microtubules attach sister chromatids to opposiute spindle poles: anaphase sister chromatids synchronously separate and the daughter chromosomes move towards the spindle poles. Kinetochore microtubules get shorter and spindle poles move outward: telophase the daughter chromosomes arrive at the two poles, and a new nuclear envelope assembles around each set. Mitotic spindle: segregates replicated chromosomes, constructed of microtubules and associated proteins. 3 classes of microtubules play a role: astral microtubules, kinetochore microtubules, overlap microtubules kinesins and dyneins also mediate the assembly and fxn of the spindle. Cytokinesis: the first visible change of cytokinesis is the appearance of a depressions cleavage furrow.