CSB331H1 Lecture Notes - Adherens Junction, Cell Junction, Tight Junction
26 Sep 2011
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Notes taken verbatim from alberts 4th and 5 edition unless otherwise noted. Cell adhesion can be subdivided into two broad categories: cell-cell and cell-matrix interactions. The cell adhesion molecules (cams) that mediate these interactions have a variety of functions beyond serving as static adhesive elements. For examples, some cams act as signal receptors that elicit changes in cell shape and gene expression. Intracellularly, these transmembrane receptors molecules are linked to complexes that play a direct role in signal transduction pathways. As with signal transduction pathway, cell adhesion involves a combination of different cams acting at the same time. The information must be integrated for proper development and tissue homeostasis to be maintained in other words, multiple parallel interactions are occurring at the same time and the information generated must be integrated. There here are six major types of tissues: Connective most text classify blood and lymphoid tissues as. Junctions are often visualized by conventional or freeze-fracture electron microscopy.
