Biology 1002B Lecture Notes - Lecture 18: Cellular Respiration, Chloroplast, Pyruvic Acid
9 Apr 2013
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Lecture 18 four most common types of cancer in canada: breast cancer, prostate cancer, lung cancer, colon cancer likely factors contributing to cancer incidence in canada role of cyclin/cdk complexes in cell cycle regulation. G1/s checkpoint: prevents cells form replicating their dna if its damaged. Damaged cells cant get through this checkpoint this checkpoint is regulated by cdk(inase). It is an enzyme that phosporylates targets, but cdks are only active when they are bound to other proteins called cyclins. Cyclins production cycles with the cell cycle (hint: the name). cyclin complex then phosphorylates a whole bunch of targets downstream and that relases the g1 checkpoint. function. Egf (epidermal growth factor receptor)- when there is egf, it binds on to this receptor and there are transmembrane domains and internal signaling domains in the protein. Egf is essential for normal embryonic growth and development (because egf is an embryo gene).
