SCIE 1P51 Lecture 10: Lecture 10.docx
15 Apr 2013
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Document Summary
In 1300, pope boniface viii issued an edict to prevent dead bodies being dismembered, to stop knights from boiling the bones of dead comrades and shipping them home to avoid burial in unconsecrated ground. This law was then interpreted to include all human dissection. Until about 3 centuries ago the human body and mind were not considered an appropriate domain for science expect that secret autopsies were performed all along in universities. Clinical trials have a long history, even if not acknowledged as clinical trials. Formal record of clinical trials dates back to time of the trialists . 1628- dr. van helmont proposed a therapeutic trial of bloodletting for fevers. Leaches or open vein and was bled into bowl. 2 dice- one black and one white: black- bloodletting, white- noxious potions. More deaths from bloodletting than the fevers. Tested different interventions on the infected sailors (vinegar meat, eating limes)
