PSYD35H3 Study Guide - Final Guide: Creb, Lamotrigine, Atypical Antipsychotic
Document Summary
Episodes don"t occur concurrently with substance, medication somatic treatments. Not due to a general medical condition. Episodes aren"t better accounted for by schizoaffective, schizophreniform, delusion, psychotic, schizo, nos. Bipolar i: at least one episode of mania. Mania symptoms: irritability, excessive high-risk activities, inflated self-esteem, distractibility, less need for sleep. Bp depression can look like mdd and schizo, bpd, adhd, substance abuse, medical conditions. Bp may be comorbid with another axis i disorder. Poorer outcome if comorbid with adhd, anciety, ocd, panic, impulse control. Suicide high in bp and bp is stable. Bp have lower life expectancy, health, 60% have comorbid substance, only 1/3 seek treatment. Usually male, psychotic features, history of alchy, poor occupational status. Bp associated with: reduction of pfc volume, decreased glial and neurons in pfc, lower levels of nna marker for neuronal health. Mood stabilizers: reverse impairment in brain structure and bdnf levels. Lithium in rats: promote neuron growth, protect neurons against toxic agents.
