Biology 1002B Lecture Notes - Lecture 5: Cell Membrane, Golgi Apparatus, Secretion

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Membranes can be more than 50% protein. Phospholipid has 2 fatty acid tails: very hydrophobic. Lots of proteins embedded in the membrane and/or interacting with the membrane. Fatty acid tails can be saturated or unsaturated. A phospholipid bilayer can be formed spontaneously -> no energy required to drive the formation. Hydrophobic tails drives the formation of the bilayer -> no biosynthetic process. You can regulate the amount of saturated/unsaturated fatty acids that you have. If unsaturated = the membrane is more fluid at the same temperature. If you unsaturate the fatty acid tail, it puts a kink in the tail. You can regulate the degree to which you have double bonds in a fatty acid. Desaturase acts on the fatty acid which can introduce carbon-carbon double bonds. If you regulate desaturase, you regulate the conversion of saturated -> unsaturated. In bacteria, high desaturase transcript when cold -> declines over time when it gets warmer.

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