BIOL 200 Lecture Notes - Lecture 2: Mutation, Proline, Noncoding Dna

• School: McGill University
• Department: Biology (Sci)
• Course: BIOL 200
• Professor: Richard Roy

Document Summary

Sugar-phosphate backbone on the outside of the double helix. Z dna is also transiently formed shortly after transcription and, as such, is a tag for actively transcribed genes: b dna can bend about its long axis. This is important in dna-protein interactions and in the folding of dna into compact condensed structures: dna denaturation and renaturation is important during dna replication and in transcription. It is also exploited in many techniques in molecular biology and genomics: tm is a function of g c content due to the extra hydrogen bond requiring more energy to break. B dna can bend about its long axis. Important in dna-protein interactions and in the folding of dna into compact condensed. Tm is a function of g c content the bond. Bases stack on top of another forming parallel planes. Orientation of the polynucleotide strands in the double helix is antiparallel.