BIOLOGY 2C03 Lecture Notes - Lecture 5: Separase, Zygote, Spermatogonium

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19 Sep 2013
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Interphase period of growth and development between cell divisions; synthesize dna, produce rna and proteins, biochemical reactions. G1 (gap 1) cell grows, cell division protein synthesis, ~10 hours: cells may enter g0 in response to regulatory signals, g0 non-dividing phase; stable state during which cells maintain constant size; remain indefinitely. S (dna synthesis) chromosomes duplicate; one chromatid sister chromatids; ~9 hours. G1/s checkpoint end of g1; checks if cell has all enzymes necessary for dna replication. G2 (gap 2) biochemical events for cell division; ~4 hours. G2/m checkpoint end of g2; checks if dna is undamaged. M (mitotic) phase (mitosis and cytokinesis) separation of sister chromatids; cell division. Prophase: chromosomes condense, chromosomes consist of two chromatids (because of dna replication in interphase) Formation of mitotic spindle (organized array of microtubules) out of centrosomes that migrate to opposite sides of the cell and contain centrioles.

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