BIOL 205 Lecture Notes - Intermediate Frequency, Product Rule, Southern Blot
27 Sep 2013
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Oct 3/2011 pg 129-134, 137-153, 163-165 function: genes present and arrangement on chromosomes are often slightly different in related species, ex. Chromosome 2 is split into 2 shorter chromosomes in great apes compared to humans: helps us deduce the evolutionary genetic mechanisms that caused these genomes to diverge. Chromosome maps tells us the arrangement of genes on chromosomes with gene positions (loci) and the distances between the loci based on some kind of scale. Recombination maps of chromosomes are assembled 2 or 3 genes at a time using linkage analysis. When 2 genes are linked, the loci of those genes are on the same chromosome and the alleles on any one homolog are physically joined by the dna between them. Bateson and punnett found a standard self of dihybrid f1, the f2 didn"t show 9:3:3:1 ratio. Certain combinations of alleles showed up more often than expected, as though they were physically attached in some way.
