BIO 181 Lecture Notes - Van Der Waals Force, Peptide, Alpha And Beta Carbon

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30 Sep 2013
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All proteins are composed of chains of roughly 21 different amino acids: numbers vary by species. Side chains differ in size, shape, chemical reactivity: those with hydroxyl, amino acid, carboxylic acid, or sulfhydryl function have more reactivity than those composed of hydrogen and carbon. Also dictate interaction with water: polar r groups form hydrogen bonds. Dissolve in water: nonpolar r groups can"t form hydrogen bonds. In water (ph 7), amino and carboxylic acid groups ionize to nh3+ and coo- respectively: makes protein more reactive, nonzwitterionic- no charges, zwitterionic- acid gives hydrogen and amine takes the hydrogen. Isomers that don"t apply to aa"s: structural- differ in order of atoms, geometric- differ in arrangements of atoms around double bond. Isomer that applies to aa"s: optical- differ in arrangement around a carbon atom that has four different groups attached, with one exception, all aa have optical isomers. Cells primarily use left-handed forms for protein.

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