PSYCH 330 Lecture Notes - Golgi Apparatus, Porosome, Exocytosis
14 Oct 2013
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Document Summary
Presynaptic cell - presynaptic membrane - synaptic cleft (space) - postsynaptic membrane - postsynaptic cell. Mitochondria and golgi bodies are found in the terminal button. Mitochondria supply energy in the form of atp. Golgi bodies are responsible for packaging and sorting proteins. Bundles of neurotransmitters are packed within synaptic vesicles. The synapse is released at the release/active zone that meets up with the postsynaptic destiny. Exocytosis is when neurotransmitters are exiting the terminal button. Once the action potential reaches the terminal button this triggers exocytosis. Positive calcium ions (more outside of the cell). Can only get into the cell through voltage gated calcium channels. Depolarization causes the voltage gated calcium channel to change shape- allowing calcium to flow into the cell. Calcium cells initiate protein cascades that move vesicles down the cell membrane and then connect with docking proteins with which the vesicles bind to. Once these vesicles break apart then opening forms called a fusion pore.
