BIOL 1000 Study Guide - Integral Membrane Protein, Cell Adhesion Molecule, Peripheral Membrane Protein
Document Summary
Lectures: cell surface receptors: signal transduction, a. Receptors embedded in plasma membrane accept a signal molecule. Signal transduction systems getting a message from call surface receptor: b. Enzyme activation, turns on/off gene transcription: signal transduction pathways, second messenger pathways/systems. Intracellular signaling pathways: all mean the same ^^^ Reception: binding of signal, 1st messenger, 2. Second messenger: small molecules, diffuse faster within cell, can be made quickly, non proteins (increase concentration rapidly, 3. It binds with only gtp: effector molecule: interacts with an activated g protein. Irreversible inhibition: inhibiting molecule covalently binds to enzyme but not a. s. causing conformational change. Poisons): allosteric control: non-competitive site binding to allosteric site, covalent modification: regulation phosphorylation, pi added to the molecule, factors affecting enzyme activity, ph. Optimal specific ph for each enzyme: temp higher temperatures call for higher activation energy, normal protein increased temp/ph/salinity denatured protein. Capacity to do work: kinetic: energy of motion, potential: energy stored (ex.