BIOL 205 Lecture Notes - Gtpase, Ultrabithorax, Prokaryotic Small Ribosomal Subunit
3 Dec 2013
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Document Summary
Expression of gene distal-less (dll) marks the start of development of appendages. Dii (blue) repressed in a1-a8 none in a1 to a8. Hox proteins repress appendage formation in the abdomen. Tells us that abdominal a keeps d out of abdominal region. Hox proteins and segment-polarity proteins control appendage location. Protein and rna molecules compose the two subunits of a ribosome. Many different points to ensure translation done with difelity. If3: binds 30s subunit and promotes dissociation of 70s ribosome, controls ability of 30s subunit to bind mrna. If2: binds and facilitats hydrolysis of gtp, recognizes fmet trna, brings to peptidyl (p) site on ribosome, all other trnas enter acceptor (a) site. If1: blocks trna from binding small subunit (future a site) Prokaryotic initiation complex forms on shine-dalgarno sequence of the mrna. If1 prevents trnas from binding to a site. If2: a gtpase binds 30s, if1 & fmet trnafmet positions on. Codon-anticodon (trna contains ainticodon) interaction 30s.
