CSB328H1 Study Guide - Final Guide: Dna Replication
25 Jan 2014
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4: missing bases knocked out of backbone, silent doesn"t affect protein made, neutral positively charged aa to positively charged. 5 1) base substitutions during replication: ways mutations occur, and how bacteria deal w it. 10: base changes from inherent chemical instability of the bases or of the n-glycosidic bond, alteration resulting from the action of other chemicals and environmental agents including oxygen, ultraviolet light, nitrites, etc. Damage through these mechanisms don"t occur during dna replication and therefore aren"t subject to proofreading or methyl-directed dna repair.
