HMB265H1 Lecture 7: Lecture 7 Readings

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25 Oct 2011
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HMB265H1 Full Course Notes
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Hemizygous gene: a gene present in only one copy in a diploid organism. Example: an x-linked gene in a male mammal. Sex linkage: the location of a gene on a sex chromosome. X linkage: the inheritance pattern of genes found on the x chromosome but not on the y chromosome. on the x chromosome. (rare) Y linkage: the inheritance pattern of genes fround on the y chromosome but not. Pseduoautosomal regions 1 and 2: small region at the ends of the x and y sex chromosomes; they are homologous and undergo pairing and crossing over at meiosis. Sex-linked inheritance regularly shows different phenotypic ratios in the two sexes of progeny, as well as different ratios in reciprocal crosses. Features: more males than females, because females can only inherit the feature if both parents have the allele. Males inherit feature when mother carries allele: affected males have offspring that don t show the phenotype.

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