PHL283H5 Lecture Notes - United States Public Health Service, Clinical Trial, Syphilis

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Azt trials background is the world aids pandemic. What was done: 16 trials in 11 countries, burkina faso, dominican republic, ethiopia o. Angels: double standard this is about as problematic as you can get when it comes to clinical research comparable to syphilis believes we have enough information for the historical studies, placebo controlled trials are unethical. May not be able to receive legitimate informed consent. Understanding can fail - differentiate between medical treatment and medical research - the risks and benefits. In a situation where there is no treatment - raise worries about the voluntary- ness of your participants: coercion. Brody: a threat to put someone below their baseline unless they co-operate with the demands of the person issuing the treat. Making someone worse off unless they listen. Different ways of understanding someone"s baseline - coercion involves making someone worse off than if the treat was never administered - factual/empirical view.

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