BIO-0013 Lecture Notes - Trans Fat, Lysosome, Glycerol

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31 Jan 2014
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Cis double bond: z9 20 12, both carbons are on the same side of the double bond o glycerol linked to 3 fatty acids by ester linkages unsaturated with cis bonds, form oils at room temp saturated with trans bonds, trans fats, solid at room temperature steroids, 4 fused carbon rings (6 6 6 5, cholesterol. 25% of membranes: sex hormones estrogen testosterone, very hydrophobic, lipid micelles can easily pass through membranes, rings of phospholipids, seen when hydrocarbon tails are short, lipid bilayers, seen with long hc tails, about 8 10 nm in width. Glucose, cl , k+, na: lipid composition changes fluidity and permeability, longer fatty acid tails decrease fluidity and permeability, increasing cholesterol content decreases fluidity and decreases permeability, unsaturated fatty acid tails (particularly those with cis double bonds) increase fluidity and increase permeability, ways to cross biological membranes, passive transport (moves with the gradient, no work is done)

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