HLTH 230 Study Guide - Methyl Group, Isoniazid, Intrinsic Factor

• School: Queen's University
• Department: Health Studies
• Course: HLTH 230
• Professor: Jeffery Lalonde

Document Summary

*corn (high in leucine) interferes with conversion of trypt. Milk, eggs, nuts, fish, whole grains, fortified and enriched grains. Role in gluconeogenesis, fa synthesis, breakdown of fa and a. a. Induced with raw egg whites (avidin -> binds to biotin, prevents absorption) Involved in making lipids, nt, steroid hormones and hemoglobin. Part of coenzyme tpp that helps energy metabolism. Part of plp and pmp used in a. a. + fa metabolism. Based on amounts needed to maintain adequate levels. In those who fail to meet energy needs. Accumulation of abnormal compounds (from tryptophan metabolism) in brain. Protein, starchy vegetables, non citrus fruits, liver, soy. *vitamin b12 + folate require each other => symbiotic relationship (depend on each other for activation) > b12 removes methyl group to activate folate. > when folate gives up methyl group to b12, b12 coenzyme becomes activated. *needs to be bound to intrinsic factor to be absorbed. Generally from poor absorption, not poor intake (2dary defic. )