Biology 2581B Lecture Notes - Lecture 5: Epistasis, Blood Type, Chi-Squared Distribution
24 Feb 2014
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Lecture 4: from genotype to phenotype deviations from mendelian ratios. Lucien cu not one of the first individuals to test mendelian principles. Looked at coat color phenotypes, was able to show that the yellow the agouti using animals allele was dominant to: however, was never ale to isolate a true-breeding yellow mouse. Should be able to isolate a homozygous yellow mouse that would give you all yellow progeny, but that never happened. Instead, matings of inbred agouti mice to yellow mice always results in a 1:1 ratio of yellow to agouti. Also an example of pleiotropy a single locus affecting two traits, yellow allele not only affects coat color, but also viablity. Pleiotropy: phenomenon in which a single gene determines a number of distinct and seemingly unrelated characteristics. Ay is dominant to a with respect to coat color. Ay is recessive to a with respect to viability.
