MIP 343 Lecture Notes - Bronchus, Chromatin, Kupffer Cell
27 Feb 2014
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Document Summary
Located in the anterior mediastinum left of the heart. Pale medulla in center consists of small lymphocytes and epithelial cells. Darker cortex consists of immature t cells which undergo maturation upon migration into the medulla, from which they enter the blood. Changes in structure during maturation and aging in humans. Lymph containing macrophages drains through the afferent lymphatic vessel into the subcapsular sinus, through the intermediate sinuses, into the medullary sinuses, and out through the efferent lymphatic vessel. Lymph follicles, containing germinal centers and a small lymphocyte mantle, are sites of. Large number of lymph follicles with germinal centers. Some t cells in germinal centers to help b cells, some b cells in medullary cords differentiating into plasma cells. Some b cells contain pink-staining immunoglobulin protein (russell bodies) Contain pale zone consisting of dendritic cells, accumulate antigen on their surface to present to lymphocytes. Darker, basophilic zone consisting of proliferating b lymphocytes.
