Anatomy and Cell Biology 3319 Chapter Notes -Schizophrenia, Lateral Globus Pallidus, Subthalamic Nucleus
3 Mar 2014
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Deep gray matter of cerebrum: consists of basal nuclei (ganglia, basal forebrain nuclei associated with. Involved in motor control memory: claustrum brain nucleus of unknown function, amygdaloid body part of limbic system. Control hierarchy: strategy/goal, association area of the cortex: Ideomotor area: basal ganglia, tactics, sequence of muscle contractions. Cerebellum: execution, activation of motor neurons. Basal forebrain nuclei: four important structures in cerebrum, septal nucleus, diagonal band (of broca, horizontal band (of broca, basal nucleus (of meynert) Parkinson"s disease: direct pathway: less excitation of. D1 receptors less inhibition/more excitation of internal globus pallidus higher inhibition of thalamus less activation of motor areas. Indirect pathway: less inhibition/more excitation of d2 receptors more inhibition of external globus pallidus less inhibition of subthalamic nuclei more activation globus pallidus higher inhibition of thalamus less activation of motor areas. Indirect pathway: higher activation of d2 neurons less inhibition of subthalamic nuclei activation of internal globus pallidus & substantia nigra less threshold to activate motor areas.
