PSY290H1 Chapter Notes - Chapter 9: Radial Glial Cell, Axon Guidance, Neural Tube

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Chapter 9 development of the nervous system: brain is a plastic (changeable) living organ, case study) genie: raised in abnormal environment, demonstrates critical role of experience in neurodevelopment. Each growing axon is attracted by the label to its postsynaptic target during neural development/regeneration. Synapse rearrangement: neurons that have established incorrect connections are likely to die: cell death results in massive rearrangement of synaptic connections- focus the output of each neuron on smaller number of postsynaptic cells thus increasing selectivity of transmission. 9. 2 ) postnatal cerebral development in human infants. Effects of experience on topographic sensory cortex maps: effects of experience on the organization of the ns come from research on sensory topographic maps. Experience fine-tunes neurodevelopment: neurons re spontaneous and begin to interact with the environment, this pattern of neural activity ne tunes subsequent stages of neurodevelopment, fine-tuning constitutes critical, nal phase of normal development.

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