LMP299Y1 Lecture Notes - Lecture 11: Hyperinsulinemia, Activin And Inhibin, Anterior Pituitary
7 Apr 2014
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Married 3 yr, trying to have child for 1 year w/o success. Bill: normal physical exam. Family history: sue"s mother had difficulty conceiving until her first child. Sue"s basal body temperature chart: monophasic ( = no ovulation) Body mass index (bmi) = weight (kg) / (height)2(m)2(normal = 20- 25: sue"s bmi: 29 (higher than normal = overweight) Level of shbg: decreased level. Definition: failure to conceive after one year of regular, unprotected intercourse: less than one year wont count. Causes of infertility: male factors, 40% of the cases. Note: assessment of male is equally important as female female factors, 50% of the cases: unknown (no abnormality found), 10% In female, endocrine abnormalities are found in 1/3 of cases: hormone dysfunction is a rare cause of male infertility. Sources: gonads (testis and ovary) and peripheral conversion (adrenal & adipose tissues) Testosterone and androgens in women: 1/2 from ovary & 1/2 from peripheral conversion of dehydroepiandrosterone (dhea) and.
