Physiology 2130 Chapter Notes -Renal Function, Distal Convoluted Tubule, Proximal Tubule
17 Apr 2014
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Module 11 - renal system: renal system includes kidneys, ureters, bladder and urethra, kidneys regulate water balance, electrolyte levels, ph of blood and long-term regulation of arterial pressure. Filtration: movement of uid through glomerular capillary due to hydrostatic pressures. Generally composed of water plus all dissolved solutes in blood (except proteins too large to be ltered) Reabsorption: movement of a substance from lumen of nephron back into blood. Secretion: movement of substance from blood into lumen of nephron. Glomerular filtration: bulk ow of uid from blood into glomerular capsule. Filtrate contains same substances as plasma with exception of large proteins & rbcs: affected by extremely permeable capillaries which make up glomerulus and starling. Forces: podocytes (epithelial cells) surround the capillaries. Glomerular filtration rate (gfr): volume of uid ltered by glomerulus during a certain time period: kidneys lter ~ 180 l/day, filtered load: amount of substances ltered by kidneys each day. Filtered load = gfr x plasma concentration of substance.
